Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

62
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
62
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

127
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
127
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

100
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
100
Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

79
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
79
Assessment of the Gastrointestinal System I: Subjective Data01:17

Assessment of the Gastrointestinal System I: Subjective Data

160
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
160
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology01:29

Gastroesophageal Reflux Disease I: Meaning and Pathophysiology

298
Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
298

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Inter-Observer Variability of Gerd-Related Metrics on High-Resolution Manometry and Calculation of the Milan Score.

Neurogastroenterology and motility·2026
Same author

Lung hernia: an updated narrative review.

Journal of thoracic disease·2026
Same author

Identification of transient hiatal hernia on high-resolution manometry is associated with gastroesophageal reflux disease.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2026
Same author

Renal Mucosa-Associated Lymphoid Tissue Lymphoma Mimicking Autoimmune Pancreatitis: A Diagnostic Challenge.

ACG case reports journal·2026
Same author

Symmetrical anterior-posterior partial fundoplication: technique and outcomes.

Surgical endoscopy·2026
Same author

Corrigendum to "Hiatal hernia and anemia: A single-center experience" [J Gastrointest Surg 30 (2026) 102333].

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2026

相关实验视频

Updated: Jun 15, 2025

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Published on: December 14, 2020

2.8K

星评分:开发和验证一种新的方法来减少不确的GERD诊断的数量.

Andrés R Latorre-Rodríguez1,2, Sumeet K Mittal3,4, Hailey Simmonds5

  • 1Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, 500 W Thomas Road, Phoenix, AZ, 85013, USA.

Surgical endoscopy
|August 27, 2024
PubMed
概括

一个新的pHoenix评分通过考虑位置性酸暴露时间 (AET) 来改善胃食道逆流症 (GERD) 诊断. 这一分数比单独的AET总数减少了不确定的病例,提供了更明确的GERD诊断.

关键词:
健行式食道pH值监测 健行式食道pH值监测格尔德 (GERD) 是一个很好的朋友.胃食道逆流是因为胃食道逆流.PH PH监测 监控 监控 监控 监控逆流是指反流,反流是指反流.

更多相关视频

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver
08:25

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver

Published on: August 27, 2021

2.5K
The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management
06:40

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management

Published on: June 29, 2019

6.6K

相关实验视频

Last Updated: Jun 15, 2025

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Published on: December 14, 2020

2.8K
Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver
08:25

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver

Published on: August 27, 2021

2.5K
The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management
06:40

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management

Published on: June 29, 2019

6.6K

科学领域:

  • 胃肠病学 胃肠病学
  • 医学诊断 医学诊断 医学诊断
  • 逆流性疾病研究研究

背景情况:

  • 约翰逊-迪梅斯特评分 (DMS) 是诊断胃食道逆流病 (GERD) 的传统基准.
  • 里昂共识定义了使用pH监测的GERD诊断,正常酸暴露时间 (AET) <4%和病态AET>6%,诊断不确定性的范围为4-6%.
  • 目前的诊断标准并没有完全解决AET (仰卧与直立) 的位置差异.

研究的目的:

  • 量化多少边界GERD病例 (AET总数4-6%) 被DMS重新分类.
  • 评估卧底AET对重新分类边界GERD病例的影响.
  • 引入一种新的综合评分,pHoenix评分,结合定位AET以改善GERD诊断.

主要方法:

  • 对114名患者进行了48小时的Bravo pH监测后期分析 (AET总数为2-6%).
  • 使用从仰卧和直立AET的回归系数开发pHoenix得分.
  • 内部验证和比较pHoenix评分对DMS和AET总的区分能力.

主要成果:

  • 该pHoenix得分显示出强大的区分能力 (AUC:0.957),具有高灵敏度和特异性.
  • 使用AET总数,77.2%的病例是边界病例;pHoenix得分将这一数字降至13.2% (p<0.001).
  • 该pHoenix得分有效地重新分类边界病例,区分正常和病态的GERD.

结论:

  • 单独的AET总体对病态反流的敏感性有限,因为它忽略了位置变化.
  • 该pHoenix得分增强了正常与病态GERD病例的差异化,减少了诊断的模两可.
  • pHoenix评分为GERD提供了更精细的诊断方法,解决了总AET和DMS的局限性.