对于第一阶层体感体感核的听觉和视觉刺激的跨模态敏感性
1Department of Physiology, Wakayama Medical University, Wakayama, Japan.
The European journal of neuroscience
|August 28, 2024
概括
腹部后侧核 (VPL) 不仅仅是用于触摸. 听觉和视觉刺激显著改变了VPL细胞的反应,证明了lamus中普遍存在的交叉模态感官相互作用.
科学领域:
- 神经科学是一个神经科学.
- 感官处理 感官处理
- 胸膜功能 胸膜功能
背景情况:
- 腹腔后侧核 (VPL) 传统上被视为一种单模体体感官处理中心.
- thalamic网状核 (TRN) 细胞表明可能对VPL神经元产生交叉模式影响.
研究的目的:
- 研究听觉和视觉刺激对麻醉大鼠VPL细胞活性的影响.
- 为了确定跨模态感官输入是否会影响VPL内的体感官处理.
主要方法:
- 采用了多细胞记录和标记技术.
- 从70个VPL细胞中获得记录,其中65个对后腿皮肤电刺激有反应.
- 听觉和/或视觉刺激与体感刺激一起呈现.
主要成果:
- 听觉或视觉刺激本身很少引起活动,除了少数双模细胞.
- 在61个VPL细胞中观察到响应大小,延迟和爆发的交叉模式变化.
- 调制取决于刺激时间,强度和频率,较短的间隔 (<800ms) 和较低频率的声音更有效.
结论:
- VPL受到来自听觉和视觉通路的显著交叉模式感官影响.
- 这些发现挑战了第一阶梯体核的单模式处理范式.
- 跨模态相互作用遍布于第一阶感官体核中.
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