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后COVID间歇性肺病:我们如何应对这个新实体?

Aycan Yüksel¹, Dilek Karadoğan², Nur Hürsoy³

¹Department of Respiratory Medicine, Başkent University Faculty of Medicine, Ankara, Türkiye

Balkan medical journal

|August 28, 2024

概括

后COVID间歇性肺病 (ILD) 影响了许多幸存者,其特点是持续的症状和肺部异常. 主动吸烟和严重的COVID-19是关键的危险因素,尽管一些患者表现出自发改善.

科学领域:

肺部病理学肺部病理学
放射学放射学是一门学科.
传染性疾病传染性疾病

背景情况:

冠状病毒疾病-2019 (COVID-19) 幸存者可能在康复后会出现持续的症状和肺部异常.
这种情况被称为COVID后间歇性肺病 (ILD) 或残留性疾病.

研究的目的:

评估COVID后的ILD的特征,风险因素和临床意义.
定义COVID后ILD的诊断标准. 为了确定COVID后ILD的诊断标准.

主要方法:

来自随机临床研究的数据的多中心横截面分析.
评估了COVID-19后3个月持久呼吸道症状的患者.
通过症状,低氧化,限制性肺功能和HRCT发现定义的COVID后ILD.

主要成果:

在375名患者中,有262名患者符合COVID后ILD的标准.
呼吸不良,运动不耐受和疲劳是常见的症状.
地面玻璃的不透明度和纤维带是HRCT经常发现的发现.
积极吸烟,ICU入院和升高的LDH是COVID后ILD的危险因素.

结论:

后COVIDILD的特点是呼吸系统症状,放射性病变和限制性肺部缺陷.
积极吸烟,严重的COVID-19和升高的LDH是显著的危险因素.
大约20%的患者在症状和放射学发现中自发改善.

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