瘤与平淡的血栓:扩散的大B细胞淋巴瘤呈现为洞腔鼻腔和左上眼动脉血栓
Hays T Cape1, Lalita Gupta1, Cody C Blanchard1
1Department of Ophthalmology and Visual Sciences, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Orbit (Amsterdam, Netherlands)
|August 28, 2024
概括
一种罕见的扩散性大B细胞淋巴瘤 (DLBCL) 病例导致瘤血栓,导致洞穴鼻腔和上眼静脉血栓. 及时诊断和用抗凝剂,类固醇和化疗治疗导致患者显著改善.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 在瘤学瘤学.
背景情况:
- 轨道和神经病变可能由各种疾病引起,包括鼻疾病.
- 洞穴鼻和上眼静脉的血栓是严重的疾病,需要及时诊断.
- 扩散性大B细胞淋巴瘤 (DLBCL) 是一种侵略性的非霍奇金淋巴瘤.
研究的目的:
- 报告一种罕见的双边洞腔鼻血栓症和由DLBCL的瘤血栓引起的上眼静脉血栓症.
- 为了突出诊断挑战和成功管理这种不寻常的演示.
主要方法:
- 一个66岁的女性患有双眼视和眼胀的病例报告.
- 最初的评估包括体检,轨道成像 (CT/MRI) 和内镜外科手术.
- 一个股质量的活检证实了DLBCL.
主要成果:
- 图像检测显示了状鼻变暗,双侧肌状鼻疾病,洞穴鼻不填充,以及左上眼动脉血栓.
- 轨道成像表明瘤血栓,后来通过下质的活检证实为DLBCL.
- 患者经历了抗凝剂,类固醇和化疗的显著改善.
结论:
- 来自DLBCL的瘤血栓可能会导致罕见的并发症,如双边洞腔鼻腔血栓症和上眼静脉血栓症.
- 涉及眼科,神经学和瘤学的多学科管理对于有利的结果至关重要.
- 这一案例强调了考虑轨道和神经病变的异常病因的重要性.
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