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Updated: Jun 15, 2025

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[关于TRAF6与神经退行性疾病之间的关系的研究进展]

Rui-Chang Luo1,2, Xin-Yi Wu1,2, Wen-Wen Yu3

  • 1Zhejiang Key Laboratory of Silkworm Bioreactor and Biomedicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.

Sheng li xue bao : [Acta physiologica Sinica]
|August 28, 2024
PubMed
概括

瘤坏死因子受体相关因子6 (TRAF6) 在神经炎症和神经退行性疾病 (NDD) 中发挥着关键作用. 它的无处不在机制对于调节阿尔茨海默氏症和帕金森病等NDD至关重要.

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Enzyme-linked Receptors01:00

Enzyme-linked Receptors

Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...
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