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Updated: Jun 19, 2026

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS
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从尿液中使用液体染色学飞行时间质谱法查广泛的药物查方法的可重复性评估

Imir G Metushi1, Michael R Wakefield2, Kara Lynch3

  • 1Department of Pathology, Center for Advanced Laboratory Medicine, University of California, San Diego Health Systems, San Diego, CA, United States.

Clinical mass spectrometry (Del Mar, Calif.)
|August 28, 2024
PubMed
概括

用于药物滥用检测的飞行时间高分辨率质谱 (TOF-HRMS) 的可重复性验证揭示了特定化合物的识别挑战. 需要进一步分析才能准确报告,特别是在不同度下.

关键词:
广泛的频谱查检查.高分辨率的高分辨率解决方案质谱测量质量谱测量毒理学 毒理学 毒理学

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Drug Concentrations: Measurements01:23

Drug Concentrations: Measurements

Drug concentration is the quantity of a drug present in a biological sample. Measuring drug amounts in biological samples allows the clinician to understand how a drug is absorbed, distributed, metabolized, and excreted. Samples can be obtained through invasive or non-invasive methods. Invasive techniques involve surgical or parenteral interventions to gather blood, cerebrospinal fluid, or tissue biopsy. Conversely, non-invasive approaches provide samples like urine, feces, and saliva.
Plasma —...