重复的负面思维对主观认知衰退的影响:对认知和大脑结构的洞察
Lídia Mulet-Pons1,2, Cristina Solé-Padullés1,2, María Cabello-Toscano1,2
1Department of Medicine, Faculty of Medicine and Health Sciences, Institute of Neurosciences, University of Barcelona, Barcelona, Spain.
Frontiers in aging neuroscience
|August 28, 2024
概括
重复的负面思维 (RNT) 与主观认知衰退 (SCD) 患者的大脑区域较薄有关. 在这个群体中,RNT会影响大脑完整性,但不会影响整体认知.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 阿尔茨海默氏症疾病研究研究
背景情况:
- 主观认知衰退 (SCD) 表明自我认知的认知障碍没有客观缺陷,造成阿尔茨海默病的风险增加.
- 重复的负面思维 (RNT) 与SCD有关,但它对SCD中大脑完整性和认知的具体影响仍未得到充分研究.
研究的目的:
- 检查RNT对中年和老年SCD患者的全球认知和大脑完整性的影响.
- 研究RNT,认知和SCD患者的大脑结构之间的相互关系.
主要方法:
- 一项横截面研究将89名SCD患者与89名匹配的对照人群进行了比较.
- 使用神经影像 (皮层厚度,白质病变) 和神经心理评估 (PACC5).
- 重复的负面思维 (RNT) 用验证的问卷进行了测量.
主要成果:
- 与对照组相比,SCD患者的RNT得分更高,右皮层厚度减少.
- 两组之间没有发现全球认知 (PACC5) 或白质病变 (WML) 的显著差异.
- 在SCD组中,RNT与皮质厚度和白质完整性正相关.
结论:
- 重复的负面思维 (RNT) 与主观认知衰退 (SCD) 患者的大脑完整性具有独特的关联.
- 研究结果支持研究心理因素,如RNT作为SCD干预的潜在目标.
- 需要进一步的研究来探索RNT在SCD相关的认知和神经变化中的调节作用.
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