炎症性血液学指数,心血管疾病和死亡率:叙述性综述
Marcela Aparecida Lopes Nascimento1, Leticia Gonçalves Resende Ferreira1, Taluane Vívian Gomes Alves1
1Universidade Federal de São João del-Rei, Divinópolis, MG - Brasil.
Arquivos brasileiros de cardiologia
|August 28, 2024
概括
炎症性血液学指数,如全身免疫炎症指数 (SII),可以预测心血管疾病 (CVD) 风险和死亡率. 这些简单的血清标记器有助于患者查和治疗指导.
科学领域:
- 心脏病学 心脏病学
- 血液学 血液学 血液学
- 炎症研究 炎症研究
背景情况:
- 心血管疾病 (CVD) 是全球主要的死亡原因之一,并造成重大经济负担.
- 慢性炎症在动脉样硬化和心血管疾病的发展中起着关键作用.
- 全血细胞计数 (CBC) 的炎症性血液学指数正在成为心血管疾病死亡率的预后因素.
研究的目的:
- 综合现有关于炎症性血液学指数与心血管风险和死亡率之间的关联的研究.
- 确定哪些特定的血液学指数与不良心血管结果最为密切相关.
主要方法:
- 在主要数据库中进行了系统的文献搜索:PubMed,Scopus,Embase,Web of Science和VHL.
- 选择了调查炎症血液学指数与心血管风险/死亡率之间的联系的研究.
- 符合条件的标准导致从最初的1,470.0人中选择了23项研究.
主要成果:
- 系统性免疫炎症指数 (SII) 显示出与整体死亡率,心血管事件和心血管死亡率的最强相关性.
- 系统性炎症反应指数 (SIRI) 也与这些结果有显著的关联.
- 血液炎症指数很容易获得,价格低廉,计算简单.
结论:
- 炎症性血液学指数,特别是SII和SIRI,是查和识别心血管事件和死亡风险高的患者的宝贵工具.
- 这些指数可以改善风险分层,指导治疗决策,并提供预后信息.
- 它们的可访问性和低成本促进了广泛的临床应用.
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