在中年和老年美国人口中,内脏脂肪和慢性阻塞性肺病的代谢得分之间的相关性
T-X Huang1, L-L Zhang, J-W Wang
1Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China. taosen666999@163.com.
内脏脂肪代谢评分 (METS-VF) 与慢性阻塞性肺病 (COPD) 患病率有积极联系. 较高的METS-VF得分表明中年和老年人患COPD的风险增加.
科学领域:
- 代谢健康 代谢健康
- 肺部医学 肺部医学
- 流行病学 流行病学
背景情况:
- 内脏脂肪的积累与各种健康问题有关.
- 内脏脂肪代谢评分 (METS-VF) 是评估腹部和内脏脂肪的新型指数.
- METS-VF与慢性阻塞性肺病 (COPD) 之间的关联仍未得到充分研究.
研究的目的:
- 调查METS-VF指数与COPD患病率之间的关系.
- 用国家健康和营养检查调查 (NHANES) 的数据分析相关性.
主要方法:
- 对NHANES 2007-2018数据进行二进制物流回归分析.
- 通过通用添加模型,值效应分析和子组分析进行验证.
- 将METS-VF和身体质量指数 (BMI) 的诊断值进行比较.
主要成果:
- 在对共变量进行调整后,观察到METS-VF和COPD患病率之间存在正相关性.
- 拥有最高METS-VF分数的个人患COPD的风险明显增加.
- 确定了一个值效应:METS-VF>7.00显示出与COPD患病率的强烈正相关性.
- 与BMI相比,METS-VF对COPD的诊断价值更高.
结论:
- METS-VF指数显示出与COPD流行率的非线性,正相关性.
- 这种关系在中年和老年美国人中显著.
- METS-VF可以作为COPD风险评估的有价值指标.
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