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在罗塔病毒感染期间,TLR3/TRIF和MAVS信号对调节粘膜T细胞反应至关重要

Rong-Rong Zhang1, Xue-Yao Yang1, Yong-Lei Yang1

  • 1College of Veterinary Medicine, Jilin Provincial Engineering Research Center of Animal Probiotics, Jilin Provincial Key Laboratory of Animal Microecology and Healthy Breeding, Engineering Research Center of Microecological Vaccines (Drugs) for Major Animal Diseases, Ministry of Education, Jilin Agricultural University, Changchun, China.

Journal of immunology (Baltimore, Md. : 1950)
|August 28, 2024
PubMed
概括

收费类受体3 (TLR3) 和TRIF信号传递对于对轮状病毒 (RV) 的适应性免疫至关重要. 丧失TLR3-TRIF会损害T细胞反应和树突细胞功能,导致RV感染期间严重的肠损伤.

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