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Updated: Jun 15, 2025

Assessing Mitochondrial Function in Sciatic Nerve by High-Resolution Respirometry
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Assessing Mitochondrial Function in Sciatic Nerve by High-Resolution Respirometry

Published on: May 5, 2022

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高糖在线粒体呼吸链缺陷中的病理作用-增加线粒体应激

Ebrima D Cham1, Tsung-I Peng2, Mei-Jie Jou1,3

  • 1Department of Physiology and Pharmacology, College of Medicine, Chang Gung University, 259 Wenhua 1st Road, Kweishan, Taoyuan 333, Taiwan.

Biology
|August 28, 2024
PubMed
概括

在NARP综合征模型中,高葡萄糖和线粒体过载会通过增加活性氧物种 (ROS) 来加剧细胞死亡. 了解这些机制可能有助于治疗神经退行性疾病.

关键词:
卡尔迪奥利平因 (cardiolipin) 是一种心脏质蛋白质.复杂的V复杂的V复杂的高葡萄糖毒性 高葡萄糖毒性这里是mROS.线粒体DNA (mtDNA) 是指线粒体的DNA.线粒体中的压力[Ca2+]m线粒体的透性过渡孔 (MPTP)氧化应激是一种氧化应激.

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