-1线

Pankaj Patyal1, Fathima S Ameer1, Ambika Verma1

  • 1Donald W. Reynolds Department of Geriatrics and Institute on Aging, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

概括

全长的Sirtuin-1 (SIRT1) 异型增强了线粒体功能和ATP的产生. 具有丢失域的替代拼接SIRT1变异显示功能减少,影响细胞代谢和基因表达.

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