口水是否真的能有效地对抗疹菌种? 这就是为什么我喜欢它
Marie Maziere1, Paulo Rompante1, José Carlos Andrade2,3
1UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS-CESPU), 4585-116 Gandra, Portugal.
Journal of fungi (Basel, Switzerland)
|August 28, 2024
概括
抗真菌药物耐药性正在上升,需要新的口服候群病治疗方法. 这项审查发现,几种欧洲口水对Candida物种表现出抗真菌的有效性,提供了潜在的治疗选择.
科学领域:
- 口腔医学是指口腔医学.
- 菌类学 菌类学是指菌类学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 口腔角膜炎是由Candida物种引起的,是一种机会性感染.
- 增加抗真菌药物耐药性限制了传统治疗的有效性,如尼斯塔丁,可纳和米可纳.
- 人们越来越需要替代性和辅助性治疗口腔候群病.
研究的目的:
- 评估和比较欧洲市场上可用的口水的体外抗真菌功效,以对抗Candida物种.
- 为了确定潜在的替代或辅助治疗口腔角膜炎.
主要方法:
- 使用PRISMA 2020指南进行了系统文献审查.
- 在PubMed和ScienceDirect数据库中进行了文献搜索.
- 包括在27年时间内发表的21项符合条件的研究.
主要成果:
- 含有chlorehexidine digluconate, cetylpyridinium 化物, hexetidine,化合物和天然抗菌剂 (薄荷醇,蒂醇,尤卡利普托尔,Glycyrrhiza glabra 提取物) 的口水表现出抗真菌活性.
- 研究中的方法差异在比较不同口水配方的疗效方面造成了模两可.
- 尽管存在差异,但几种欧洲口水显示出潜在的抗疹作用.
结论:
- 某些商业上可用的欧洲口水具有抗真菌特性,可以对抗Candida物种.
- 这些口水可以作为预防和治疗口腔候群病的有价值的工具,特别是在抗真菌耐药性上升的背景下.
- 需要进一步进行标准化研究,以最终比较各种口水配方的疗效.
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