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Updated: Jun 15, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

Published on: May 15, 2019

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本佐[a]氧化合物的抗癌活性 促进溶酶体功能障碍

João Carlos Canossa Ferreira1,2,3, M Sameiro T Gonçalves3, Ana Preto1,2

  • 1Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.

Cells
|August 28, 2024
PubMed
概括

新型[a]氧衍生物C9,A36和A42显示为向癌症治疗的前景. 这些化合物通过破坏 lysosomes 选择性地诱导癌细胞死亡,为乳腺和结直肠癌治疗提供了一种新方法.

关键词:
尼罗河蓝的类似物.抗癌药物是一种抗癌药物.子[a]氧氨酸 (Benzo[a]phenoxazine) 是一种氧氨酸.乳腺癌 乳腺癌 乳腺癌结肠直肠癌是什么意思溶酶体膜透性化 溶酶体膜透性化

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