Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A shared mechanism in eye optical development: Lens nucleus centralization in Xenopuslaevis.

Experimental eye research·2026
Same author

Estrogen Stabilizes Interferon-Inducible Genes During Skeletal Muscle Regeneration.

Biological research for nursing·2025
Same author

A Conserved Mechanism in Eye Optical Development: Lens Nucleus Centralization in <i>Xenopus laevis</i>.

bioRxiv : the preprint server for biology·2025
Same author

Proteomic and <i>N</i>-glycomic comparison of synthetic and bovine whey proteins and their effect on human gut microbiomes <i>in vitro</i>.

Microbiology spectrum·2025
Same author

Notch Is Required for Neural Progenitor Proliferation During Embryonic Eye Regrowth.

International journal of molecular sciences·2025
Same author

Biophysics at the edge of life and death: radical control of apoptotic mechanisms.

Frontiers in cell death·2025

相关实验视频

Updated: Jun 15, 2025

Microinjection of DNA into Eyebuds in Xenopus laevis Embryos and Imaging of GFP Expressing Optic Axonal Arbors in Intact, Living Xenopus Tadpoles
06:32

Microinjection of DNA into Eyebuds in Xenopus laevis Embryos and Imaging of GFP Expressing Optic Axonal Arbors in Intact, Living Xenopus Tadpoles

Published on: September 4, 2019

6.2K

发展中的Xenopus laevis眼睛的时间转录基因分析.

Samantha J Hack1, Juli Petereit2, Kelly Ai-Sun Tseng3

  • 1Department of Biological Sciences, Western Michigan University, Kalamazoo, MI 49008, USA.

Cells
|August 28, 2024
PubMed
概括

这项研究绘制了Xenopus.在发育和再生过程中视网膜原生细胞 (RPC) 的分子特征. 了解RPC基因表达对于开发视力障碍治疗方法至关重要.

关键词:
没有口,没有口.这是Xenopus.细胞信号传递是细胞的信号传递.眼睛的发育 眼睛的发育眼睛转录组 (ocular transcriptome) 是一个转录组.视网膜 视网膜 视网膜 是一个视网膜的原始细胞细胞.

更多相关视频

Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo
11:13

Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo

Published on: February 2, 2016

8.0K
Dissection, Culture, and Analysis of Xenopus laevis Embryonic Retinal Tissue
10:22

Dissection, Culture, and Analysis of Xenopus laevis Embryonic Retinal Tissue

Published on: December 23, 2012

13.8K

相关实验视频

Last Updated: Jun 15, 2025

Microinjection of DNA into Eyebuds in Xenopus laevis Embryos and Imaging of GFP Expressing Optic Axonal Arbors in Intact, Living Xenopus Tadpoles
06:32

Microinjection of DNA into Eyebuds in Xenopus laevis Embryos and Imaging of GFP Expressing Optic Axonal Arbors in Intact, Living Xenopus Tadpoles

Published on: September 4, 2019

6.2K
Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo
11:13

Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo

Published on: February 2, 2016

8.0K
Dissection, Culture, and Analysis of Xenopus laevis Embryonic Retinal Tissue
10:22

Dissection, Culture, and Analysis of Xenopus laevis Embryonic Retinal Tissue

Published on: December 23, 2012

13.8K

科学领域:

  • 发展生物学 发展生物学
  • 眼科医生 眼科 眼科
  • 基因组学就是基因组学.

背景情况:

  • 视网膜原生细胞 (RPC) 产生所有视网膜细胞类型.
  • 了解RPC分子签名对于治疗视力障碍至关重要.

研究的目的:

  • 在Xenopus的视网膜发生过程中定义RPC的转录组概况.
  • 为了确定RPC增殖和分化的分子调节者.

主要方法:

  • 在三个胚胎阶段对整个Xenopus眼睛的RNA测序.
  • 不同基因表达分析.
  • 基因本体学和KEGG通路分析.

主要成果:

  • 在RPC增殖过程中对发育途径 (Wnt,刺) 的调节.
  • 在分化过程中丰富代谢和光传导基因.
  • 保存的眼睛再生基因的表达 (sox2,pax6,nrl,Notch信号传递).

结论:

  • 这项研究为视网膜生成期间的RPCs提供了全面的转录基因资源.
  • 确定了关键的发育和再生基因,为RPC调节提供了洞察力.
  • 这一数据集有助于未来对眼睛修复和再生机制的研究.