在腹腔透析患者中估计饮食中的蛋白质和摄入量与去除
Ana Bontić1,2, Aleksandra Kezić1,2, Jelena Pavlović1,2
1Clinic for Nephrology, University Clinical Center of Serbia, Pasterova 2, 11000 Belgrade, Serbia.
Metabolites
|August 28, 2024
概括
饮食中较高的蛋白质摄入量会增加腹膜透析患者的摄入量和心血管风险. 监测摄入量和提取量至关重要,特别是在残留功能下降的情况下.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 心血管健康 心血管健康
- 营养科学 营养科学
背景情况:
- 腹腔透析 (PD) 患者的饮食蛋白质摄入量增加与更高的摄入量和心血管风险有关.
- 透析和尿路去除 (DSR/USR) 是评估摄入量的潜在标志物.
- 剩余功能 (RRF) 和并发症等级影响去除和蛋白质代谢.
研究的目的:
- 分析DPI和PD患者的摄入量之间的相关性.
- 为了研究RRF,并发症等级,去除和蛋白质代谢之间的关联.
- 确定增加蛋白质摄入量对平衡和患者结局的影响.
主要方法:
- 一个单一中心的横截面研究,涉及60名流行PD患者.
- 对饮食中的蛋白质摄入量 (DPI),摄入量,去除 (DSR,USR,TSR),正常化蛋白质代谢率 (nPCR),瘦体质量 (LBM) 和戴维斯并发症评分的分析.
- 统计分析以确定这些参数之间的相关性和关联.
主要成果:
- 下部RRF (<2mL/min/1.73m2) 与减少的USR和LBM相关.
- 患有较高DPI (>0.8g/kg/day) 的患者表现出更高的摄入量和nPCR.
- 蛋白质摄入量与摄入量有显著的相关性,而摄入量与总去除 (TSR) 有很强的相关性.
结论:
- 增加饮食中的蛋白质摄入需要对PD患者的摄入量和提取量进行仔细监测.
- 保持残留的功能对于有效的去除和保持瘦体质量至关重要.
- 了解这些关系可以帮助减轻PD患者的心血管风险.
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