自我感知的生活质量,在肌缩侧面硬化症的认知和行为障碍
Ratko Radakovic1,2,3,4, Amy Carroll5,6, Alair Altiero7
1Department of Clinical Psychology and Psychological Therapies, Norwich Medical School, University of East Anglia, Norwich, UK. r.radakovic@uea.ac.uk.
Journal of neurology
|August 28, 2024
概括
行为障碍显著影响肌缩性侧面硬化症 (ALS) 患者的生活质量 (QoL),影响情绪和社会互动. 认知和行为障碍会影响ALS中的特定QoL域.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
背景情况:
- 自我感知的生活质量 (QoL) 对肌缩性侧面硬化症 (ALS) 患者至关重要.
- 照顾者负担与认知和行为障碍有关,但它们对ALS QoL子域的直接影响仍未得到充分研究.
研究的目的:
- 研究ALS患者的认知和行为障碍与特定的QoL领域之间的关系.
- 使用疾病特异性措施来评估这些损害对QoL的影响.
主要方法:
- 使用现有的专业ALS诊所数据进行定量,横截面,观察性队列研究.
- 数据包括临床,人口,ALS特异性 QoL 简短形式 (ALSsQoL-SF) 和爱丁堡认知和行为ALS屏幕 (ECAS) 的结果.
- 进行了组对比和回归分析.
主要成果:
- 在121名ALS参与者中,61.2%的人表现出认知和/或行为障碍.
- 行为障碍 (ALSbi) 与负面情绪和社会互动领域的较低QoL相关.
- 综合认知和行为障碍 (ALScbi) 与亲密领域的 QoL 降低有关.
结论:
- 在ALS患者中,行为障碍显著影响特定的QoL子域.
- 这些领域包括内化 (负面情绪) 和外化 (社会互动,亲密) 领域.
- 认知和行为障碍是ALS QoL的关键预测因素.
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