一个名字有什么意思? 在前十字带重建随机对照试验中定义"失败":系统性审查
Vincent Milantoni1, Praveen Sritharan2, Hassaan Abdel Khalik3
1Faculty of Health Sciences, McMaster University, Hamilton, Canada.
Current reviews in musculoskeletal medicine
|August 28, 2024
概括
前十字带重建试验缺乏对移植失败的明确定义. 这次审查突出了不一致性,并呼吁制定一个包含客观和主观参数的通用定义,以改善医疗实践和研究.
科学领域:
- 整形外科手术 整形外科手术
- 运动医学 运动医学
- 临床试验 临床试验
背景情况:
- 移植失败是前十字带 (ACL) 重建的常见结果.
- 目前的随机对照试验 (RCT) 缺乏对ACL移植失败的共识定义.
- 不一致的定义阻碍了比较分析和临床决策.
研究的目的:
- 系统地审查和总结目前用于RCT中ACL移植失败的定义和参数.
- 为了确定定义ACL移植缺陷的共同标准和不一致性.
- 为制定ACL移植失败的标准化定义提供信息.
主要方法:
- 与ACL重建相关的随机对照试验 (RCT) 的系统审查.
- 分析了40项涉及4466名参与者的研究.
- 用于定义移植缺陷的参数的分类和合成.
主要成果:
- 在RCT中对ACL移植失败的定义存在重大不一致.
- 异常的膝盖松 (80%) 和移植重裂 (37.5%) 是最常见的参数.
- 只有90%的研究正式定义或引用了移植失败的病因.
结论:
- 对ACL移植失败的普遍定义对于医疗实践和研究清晰度至关重要.
- 建议采用一个复合的结果测量方法,包括客观的 (例如,重裂) 和主观的 (例如,验证的问卷) 参数.
- 本综述为骨科外科医生提供了基础,以建立ACL移植失败的正式定义.
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