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Updated: Jun 15, 2025

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication
05:33

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication

Published on: July 5, 2024

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在点击链接模板上的易发生错误的DNA合成

A V Endutkin1, A O Yakovlev1,2, T D Zharkov1

  • 1Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia.

Doklady. Biochemistry and biophysics
|August 28, 2024
PubMed
概括

点击结合在DNA中产生三醇链接,该链接抵抗修复酶,但导致DNA聚合酶停滞或错误纳入基. 这表明点击结合可能会在定制基因合成过程中引发重大错误.

关键词:
在AP的内核酶中,这种DNA聚合酶是DNA聚合酶.修复DNA的修复DNA的修复然后点击化学.突变是发生在突变中的突变.复制复制复制复制复制复制复制

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