衰老细胞通过SASP-脂质15d-PGJ2介导的HRas修饰和控制来抑制小鼠肌细胞分化

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Updated: Jun 15, 2025

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Published on: August 12, 2018

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Swarang Sachin Pundlik1,2, Alok Barik1, Ashwin Venkateshvaran1

  • 1Metabolic Regulation of Cell Fate (RCF), Institute for Stem Cell Science and Regenerative Medicine (InStem), Bangalore Life Science Cluster, Bengaluru, India.

eLife
|August 28, 2024
PubMed
概括

衰老细胞释放脂质15d-PGJ2,这会损害化疗后骨肌肉的再生. 抑制其产生恢复肌肉分化,为化疗引起的组织损伤提供治疗点.

关键词:
作为HR,作为HR.在 SASP 找 SASP生物化学 生物化学化学生物学 化学生物学这里是鼠标鼠标鼠标鼠标鼠标鼠标.肌肉分化 肌肉分化氧利平素是一种氧利平素.衰老是一种老化.

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