微生物生长的比较在不同的环境中使用不同的原始化溶液在原始化的体外膜氧化电路上
Berenice Godinez1, Allison Weinberg2, Ramsha Azmat3
1Transfusion Medicine Technologist, University of Chicago, Chicago, IL, USA.
Perfusion
|August 28, 2024
概括
带的体外膜氧化 (ECMO) 电路在56天内保持无菌,无论储存环境或原始化溶液如何. 这一发现支持目前在重症监护机构的应急准备现行做法.
科学领域:
- 心血管和呼吸科学 心血管和呼吸科学
- 医疗设备无菌性 医疗设备无菌性
- 关键护理医学 关键护理医学
背景情况:
- 体外膜氧化 (ECMO) 对于严重的心脏/肺衰竭至关重要.
- 在紧急情况下,ECMO的立即反应至关重要.
- 启动电路节省时间,但它们的无菌性尚未得到充分研究.
研究的目的:
- 评估储存环境和原料溶液对原料ECMO电路中的微生物生长的影响.
- 为了确定初始化ECMO电路保持无菌性的最大持续时间.
主要方法:
- 组装和启动了12个成年ECMO电路.
- 电路被储存在无菌和非无菌环境中.
- 原始化溶液包括普通盐水 (NaCl) 和Plasmalyte-A.
- 无菌性被测试了56天,使用厌氧瓶培养物检测特定的病原体.
主要成果:
- 在任何测试电路中都没有观察到黄金葡萄球菌, Pseudomonas aeruginosa 或 Escherichia coli 的微生物生长.
- 储存环境 (无菌与非无菌) 并没有影响电路无菌性.
- 原始溶液 (NaCl与Plasmalyte-A) 没有影响ECMO电路的无菌性.
结论:
- 带有头的ECMO电路可以安全存储长达56天,没有检测到细菌生长的证据.
- 在此时间内,存储条件和原始溶液不会影响ECMO电路的无菌性.
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