血管光滑肌细胞中的胰岛素受体调节动脉样硬化的斑块稳定性

Qian Li1,2, Jialin Fu1,2, Kyoungmin Park1,2

  • 1Dianne Nunnally Hoppes Laboratory for Diabetes Complications, Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA 02215, USA.

Cardiovascular research
|August 28, 2024
PubMed
概括

胰岛素抵抗通过损害血管光滑肌细胞 (VSMC) 功能,促进不稳定的动脉样硬化斑块. 在VSMC中失去胰岛素受体 (IR) 会增加炎症和亡,导致斑块不稳定.

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