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Updated: Jun 15, 2025

Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis
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肌肉胆固醇运输的调节失调在肌缩性侧面硬化症中

Delphine Sapaly1, Flore Cheguillaume1, Laure Weill1

  • 1University Paris Cité and Inserm UMR_S1124, 75270, 75006 Paris, France.

Brain : a journal of neurology
|August 28, 2024
PubMed
概括

胆固醇在患有肌性侧面硬化症 (ALS) 的患者的骨肌肉中积累,与疾病严重程度相关. 这种与NPC1/2载体相关的失调,发生在症状前,可能为ALS提供治疗点.

关键词:
疾病的进展 疾病的进展代谢 代谢 代谢 代谢症状前阶段 症状前阶段

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