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在机械吸气-排气过程中,上空气道和喉阻力
Tiina M Andersen1, Anne Kristine Brekka1, Zoe Fretheim-Kelly2
1Thoracic Department, Haukeland University Hospital, Bergen, Norway; The Faculty of Health and Social Sciences, Western Norway University of Applied Science, Bergen, Norway.
机械吸气-排气 (MI-E) 可以用于计算上呼吸道和喉阻力. 研究结果表明,调整MI-E压力,使用较低的吸气和较高的负压,以提高疗效.
科学领域:
- 呼吸系统生理学 呼吸系统生理学
- 生物医学工程 生物医学工程
背景情况:
- 机械吸气-排气 (MI-E) 有助于分泌物清除,但可以受到上呼吸道反应的阻碍.
- 在MI-E期间了解上呼吸道压力传输动态对于优化其有效性至关重要.
研究的目的:
- 为了确定MI-E期间是否可以计算空气流阻力.
- 研究MI-E期间压力如何传递到气管.
主要方法:
- 一项涉及10名健康成年人的横截面研究.
- 应用MI-E在不同的压力设置下,有或没有活跃的咳.
- 在面罩上,喉上方和气管中测量了气流和压力.
主要成果:
- 阳性气管压力被有效地传递;负压力约占设置的50%.
- 上呼吸道阻力 (Ruaw) 超过了喉间阻力 (Rtl).
- 参与者的努力和喉关闭显著影响了气管压力和阻力.
结论:
- 在MI-E期间,可以切实计算空气流阻力 (Ruaw和Rtl).
- 压力传递不同于正压和负压,受患者的努力的影响.
- 临床建议包括使用较低的吸气和较高的负压来治疗MI-E.
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