囊性纤维化患者的空经验:系统性审查
Fiona O'Leary1, Niamh Coffey1, Francis M Burke1
1Cork University Dental School & Hospital, Wilton, Cork, Ireland.
Journal of dentistry
|August 28, 2024
概括
患有囊性纤维化 (CF) 的儿童通常比健康儿童有较低的虫体验. 然而,患有CF的成年人表现出更高的牙经验,这表明需要为这一群体量身定制的牙科护理方法.
科学领域:
- 口腔健康研究 口腔健康研究
- 遗传学和疾病
- 系统审查方法论系统审查方法论
背景情况:
- 囊性纤维化 (CF) 是一种由CFTR基因突变引起的多系统遗传疾病.
- 有限的数据存在于口腔健康状况,特别是空的经验,在CF的个体.
- 本系统性综述解决了有关CF患者空患病率的知识差距.
研究的目的:
- 系统地审查和评估现有的关于CF患者空经验的文献.
- 为了在不同年龄段的CF患者和非CF患者之间比较脏的经验.
- 确定与CF相关的口腔健康结果的趋势和潜在差异.
主要方法:
- 在五个主要的在线数据库中进行了全面的文献搜索:Embase,Scopus,Web of Science核心集合,Medline Ebsco和Cochrane图书馆.
- 在被诊断为CF的个体中报告脏经历的研究被纳入分析.
- 对所选的研究进行了定性分析.
主要成果:
- 最初的搜索产生了1199篇论文,最终的定性分析包括了21项研究.
- 与对照人群相比,14项研究表明,CF儿童的皮肤损伤率较低.
- 五项研究报告了CF成年人患有较高的皮经验,而两项研究发现了不确定的结果. 在所有纳入的研究中都注意到存在偏差风险.
结论:
- 一个明显的趋势表明,患有CF的儿童比健康的同龄人牙腐烂较少.
- 相反,患有CF的成年人与非CF个体相比,表现出较高的脏病患病率.
- 专注于成年CF群体的进一步研究至关重要,牙医应该为CF患者采取专门的护理策略.
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