控制营养状况 (CONUT) 评分预测手术治疗结肠癌患者的术后风险和预后:一项回顾性研究.
Federico Cozzani1,2, Matteo Ricchiuto1,2, Edoardo Virgilio3,2
1Department of Medicine and Surgery, University of Parma, Parma, Italy.
Anticancer research
|August 28, 2024
概括
控制营养状况 (CONUT) 评分预测结肠癌 (CC) 患者的结果. 较低的CONUT得分与更少的并发症,更短的住院时间和CC手术后更好的生存率有关.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 营养科学 营养科学
背景情况:
- 控制营养状况 (CONUT) 评分评估了手术前的营养状况.
- 现有研究经常将结肠癌 (CC) 和直肠癌 (RC) 组合在一起,尽管它们具有不同的特征.
- 缺乏专注于CONUT得分的预测价值的研究,特别是在手术CC患者中.
研究的目的:
- 评估CONUT得分对仅为结肠癌 (CC) 进行手术的患者的术后病程和生存的预测作用.
- 为了确定CONUT得分是否可以在CC患者队列中区分结果,独立于其他临床病理因素.
主要方法:
- 在2013年至2018年间接受手术的341名CC患者的回顾性分析.
- 使用了淋巴细胞,总胆固醇和白蛋白的血清水平来计算CONUT得分.
- 采用简化的两级CONUT分类:低分 (<3) 和高分 (≥3).
主要成果:
- 与高分数患者相比,具有较低CONUT分数的患者经历的术后并发症 (手术和非手术) 显著减少.
- 较低CONUT分数组的平均住院时间较短 (11.2天对15天).
- 较低的CONUT得分与整体存活率和无病存活率的统计学显著改善有关.
结论:
- 康得分 (CONUT) 是预测术后结果和结肠癌 (CC) 治愈手术患者的存活率的一个有价值的工具.
- 建议对CONUT参数进行系统的术前评估和纠正 (例如通过人工营养),以改善患者的预后.
- 这项研究支持使用CONUT得分作为CC的独特预后指标,与RC分开.
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