肺部Mycobacterium heckeshornense感染,其中引起的微生物很难识别
Yoshihiro Kobashi1, Satoshi Mitarai2, Toru Oga1
1Department of Respiratory Medicine, Kawasaki Medical School, Japan.
Internal medicine (Tokyo, Japan)
|August 28, 2024
概括
一个患有克罗恩氏病的女性出现了肺腔. 鉴定了mycobacterium heckeshornense,导致肺部感染的诊断和成功的抗生素治疗.
科学领域:
- 肺部医学 肺部医学
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 克罗恩氏病患者容易感染机会性感染.
- 克罗恩病的肺部并发症可以模仿其他疾病.
- 非结核性真菌细菌感染是一个新兴的问题.
研究的目的:
- 报告一个罕见的肺部Mycobacterium heckeshornense疾病病例.
- 为了突出免疫受损患者的诊断挑战.
- 描述成功的治疗结果.
主要方法:
- 胸部计算机断层扫描 (CT) 用于初始成像.
- 用CT指导的肺活检用于组织病理学分析.
- 支气管镜与支气管膜洗用于微生物识别.
- 酸速细菌涂抹和培养以检测菌根菌.
主要成果:
- 胸部CT显示了一个透的阴影与右上叶的空洞.
- 肺活检显示了上皮质质粒瘤;酸快细菌涂抹呈阳性,但培养是负面的.
- 黑角菌菌 (Mycobacterium heckeshornense) 被从支气管支气管洗液中分离出来.
- 肺部M. heckeshornense疾病被诊断为.
- 用异化,利芬素和乙胺醇治疗导致了改善.
结论:
- 肺部Mycobacterium heckeshornense感染是一种罕见但可治疗的疾病.
- 早期诊断和适当的抗微生物治疗对于有利的结果至关重要.
- 这一案例强调了在免疫功能低下,肺部透患者中考虑非典型的真菌细菌感染的重要性.
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