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Updated: Jun 14, 2025

Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols
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通过GRK2介导的AKT激活以p53依赖的方式控制细胞周期进展和G2检查点

Verónica Rivas1,2, Teresa González-Muñoz1,2, Ángela Albitre1,2

  • 1Departamento de Biología Molecular, IUBM-UAM and Centro de Biología Molecular "Severo Ochoa" (UAM-CSIC), Madrid, Spain.

Cell death discovery
|August 28, 2024
PubMed
概括

细胞循环检查点可以阻止DNA损伤的进展. GRK2下调阻止PI3K/AKT激活,允许线粒分裂,而p53集成GRK2信号用于瘤细胞存活.

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