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Updated: Jun 14, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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根据eIF5A的P53依赖性低化影响线粒体翻译和衰老免疫监测

Xiangli Jiang1,2, Ali Hyder Baig1, Giuliana Palazzo1,3

  • 1Translational Control and Metabolism, German Cancer Research Center (DKFZ), Heidelberg, Germany, Heidelberg, Germany.

Nature communications
|August 28, 2024
PubMed
概括

细胞衰老涉及到永久的生长停止. 这项研究揭示了真核细胞启动因子5A (eIF5A) 驱动衰老细胞中的蛋白质合成增加,影响免疫监测.

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