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Updated: Jun 14, 2025

Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution
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Published on: January 16, 2017

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RPA将RNase H1转化为双向外原核酶,用于过程性RNA-DNA混合裂变

Yanan Li1, Chao Liu2,3, Xinshuo Jia1

  • 1School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

Nature communications
|August 28, 2024
PubMed
概括

这项研究揭示了Saccharomyces cerevisiae RNase H1在RNA-DNA杂交物上表现出令人惊的3'到5'外原核酶活性. 复制蛋白A增强了这种活动,揭示了对核酸代谢的新见解.

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