严重的支气管切除与心血管内膜介质厚度增加有关
Wang Chun Kwok1, Kui Kai Lau1,2, Kay Cheong Teo1
1Department of Medicine, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, Pokfulam, Hong Kong SAR, China.
BMC cardiovascular disorders
|August 28, 2024
概括
严重的支气管切除与增加的亚临床动脉样硬化有关,通过心脏内膜介质厚度 (CIMT) 测量. 轻度至中度支气管切除症在CIMT与对照组相比没有显著差异.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 医疗成像医学成像
背景情况:
- 支气管切除与心血管疾病有关.
- 有限的证据存在于支气管切除和亚临床动脉样硬化,特别是动脉内膜介质厚度 (CIMT).
研究的目的:
- 为了比较有支气管切除症和没有支气管切除症的患者的CIMT.
- 评估支气管切除症严重程度 (使用FACED评分) 和CIMT之间的关联.
主要方法:
- 在香港一家医院进行的前性研究.
- 招募了155名患有非囊性纤维化支气管切除症的中国患者和512名对照患者.
- 使用多变量线性回归测量CIMT并分析数据.
主要成果:
- 平均CIMT为0.58±0.10毫米 (对照组),0.63±0.11毫米 (轻度至中度支气管炎症) 和0.66±0.08毫米 (严重支气管炎症).
- 轻度至中度支气管切除症患者和对照组之间没有显著的CIMT差异.
- 与对照组相比,严重支气管切除症患者的CIMT显著增加,即使没有先前的心血管疾病或风险因素.
结论:
- 亚临床动脉样硬化,由增加的CIMT表明,在患有严重支气管切除症的患者中更为普遍.
- 轻度至中度的支气管切除症没有与增加的CIMT显著相关.
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