欧洲肺高血压的死亡率2001-2019年
Adam Hartley1,2, Harpreet Singh3,4, Chinmay Jani3,5,6
1National Heart and Lung Institute, Imperial College, Hammersmith Hospital, London, UK. adam.hartley12@imperial.ac.uk.
2001-2019年期间,欧洲肺高血压 (PH) 的死亡率增加,特别是在女性中. 然而,肺动脉高血压 (PAH) 死亡率在女性中下降,突出数据可靠性问题.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 肺高血压 (PH) 和肺动脉高血压 (PAH) 的发病率正在上升,与患者的不良结果有关.
- 准确的死亡率数据对于了解疾病负担和趋势至关重要.
研究的目的:
- 分析2001年至2019年欧洲PH和PAH年龄标准化死亡率 (ASMR) 的趋势.
- 评估公开可用的PH和PAH死亡统计数据的可靠性.
主要方法:
- 从世卫组织死亡数据库 (PH和PAH的ICD-10代码) 中提取了18岁以上个体的ASMR数据.
- 包括英国和欧盟国家,人口>100万和>75%的数据可用性从2001-2019年.
- 在男性和女性中分析了PH和PAH的中位数ASMR变化.
主要成果:
- 在可用的欧洲国家中,PH ASMR的中位数在女性中增加了22.51%,在男性中增加了6.06%.
- 在女性中,PAHASMR的中位数下降了28.74%,在男性中略有增加了1.07%.
- 观察到国家间的显著差异,一些东欧国家表现出不一致的趋势.
结论:
- 公共可用的PH死亡率统计可能缺乏可靠性.
- 欧洲的整体PH死亡率似乎在增加,而PAH死亡率在女性中呈现下降趋势.
- 强调急需改进,高质量的死亡报告和PH和PAH的国际登记册.
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