伊基盖与血清高脂胆固醇水平的纵向变化之间的关系:社区循环风险研究 (CIRCS)
Shiori Ikeda1, Ai Ikeda1,2, Kazumasa Yamagishi1,3,4
1Department of Public Health, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Lipids in health and disease
|August 28, 2024
概括
这项研究发现,具有伊基盖感的女性具有更高的高密度脂蛋白胆固醇 (HDLC) 水平. 这些HDLC的差异在女性中持续了八年,但在男性中没有.
科学领域:
- 心血管健康 心血管健康
- 心理健康 心理健康
- 生物标志物 生物标志物
背景情况:
- 积极的心理健康与血清高密度脂蛋白胆固醇 (HDLC) 有关.
- 之前没有进行过纵向研究来调查ikigai和血清hdlc之间的关联.
- 这项研究通过检查 Ikigai 随着时间的推移对 HDLC 的影响来弥补这一差距.
研究的目的:
- 为了研究伊基盖和血清HDLC水平之间的纵向关联.
- 为了确定伊基盖是否会影响血清HDLC在8年内发生的变化.
- 为了探索伊基盖-HDLC关系中的潜在的性别差异.
主要方法:
- 利用了2010-2018年的队列数据集,包括471名男性和776名女性,年龄在40-74岁之间.
- 使用自我报告的类别来评估ikigai水平:"有ikigai"",有点ikigai"和"没有ikigai".
- 使用直接方法测量血清HDLC,使用线性混合效应模型分析数据.
主要成果:
- 与没有Ikigai的女性相比,患有Ikigai的女性的血清HDLC基线显著更高.
- 患有伊基盖的女性血清HDLC的这些差异在整个八年随访期间持续存在.
- 在男性中,Ikigai和血清HDLC水平之间没有显著的关联.
结论:
- 女人对伊基盖的感觉与较高的血清HDLC水平有关.
- 在八年观察期间,女性的这种关联始终保持一致.
- 这些发现表明,心理健康 (Ikigai) 和心血管生物标志物 (HDLC) 之间存在潜在的性别特异关系.
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