在轻度后的COVID-19患者中评估肺动脉硬性:试点前性研究
Yetkin Korkmaz1, Tufan Çınar1, Faysal Şaylık2
1Department of Cardiology, Sultan II. Abdulhamid Han Training and Research Hospital, Istanbul, Türkiye.
Journal of cardiovascular imaging
|August 28, 2024
概括
以前患有COVID-19感染的个体表现出肺动脉硬度 (PAS) 的增加,这是早期肺血管变化的关键指标. 这表明需要对COVID-19后患者进行肺高血压监测.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 评估COVID-19后非住院患者的早期肺血管变化.
- 利用肺动脉硬度 (PAS) 作为这些变化的生物标志物.
研究的目的:
- 在没有住院治疗的COVID-19病史患者中调查肺动脉硬度升高 (PAS).
- 确定PAS是否可以作为COVID-19后肺血管变化的早期指标.
主要方法:
- 对201名非住院COVID-19幸存者和195名健康对照者的前性分析.
- 通过将平均峰值肺流速度除以肺流加速时间来计算PAS.
主要成果:
- 在COVID-19后的参与者表现出明显更高的PAS (10.2 ± 4.11 Hz/msec) 与健康对照组相比 (8.56 ± 1.47 Hz/msec;P < 0.001).
- 肺动脉加速时间在COVID-19后的组中明显较低.
- 多变量分析证实PAS是之前COVID-19疾病的显著预测因素 (OR,1.267;P<0.001).
结论:
- 这项研究是首次报告与对照组相比,在有COVID-19病史的人群中,PAS水平较高.
- 升高的PAS表明在COVID-19后期有可能发展为肺动脉高血压.
- 建议COVID-19幸存者定期对肺动脉高血压进行随访.
相关概念视频
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
01:20COPD: Pathogenesis and Clinical Features
244
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
244
01:22Chronic Obstructive Pulmonary Disease
1.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.2K
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.7K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.7K
01:25Pulmonary Function Tests
312
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
312
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.7K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.7K