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Updated: Jun 14, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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作为p53突变体的潜在激活剂的金胺三元体

Maryam M Jebril Fallatah1, Özlem Demir2, Fiona Law1

  • 1Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA.

Biomolecules
|August 29, 2024
PubMed
概括

研究人员确定了UCI-1001,该化合物可以恢复癌细胞中突变p53 (关键瘤抑制剂) 的功能. 这种候选药物通过重新激活野生类型的p53活动,显示出对个性化癌症治疗的希望.

关键词:
这就是CETSA.在DSF中,DSF是DSF.癌症 癌症 癌症 癌症 癌症突变的 p53 变种在 p53 校正器中使用 p53 校正器.p53重新激活器的使用方法这是一种瘤抑制剂.

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