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Updated: Jun 14, 2025

A High-content Imaging Workflow to Study Grb2 Signaling Complexes by Expression Cloning
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用 Affimer 蛋白准 Grb2 SH3 域提供了对 Ras 信号调制的新见解

Anna A S Tang1, Andrew Macdonald1,2, Michael J McPherson1,2

  • 1School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.

Biomolecules
|August 29, 2024
PubMed
概括

新的affimer试剂准增长因子受体结合蛋白2 (Grb2) SH3域. 仅仅抑制C端SH3域就会抑制Ras信号传递,这表明Grb2-SOS1相互作用的全调节.

关键词:
蜂信号传输是如何实现的蛋白质领域的蛋白质域.蛋白质蛋白质相互作用

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