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Updated: Jun 14, 2025

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
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Published on: July 17, 2020

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通过蛋白质合成的强化 诱导者在PTEN异型中致病性早期终结子的转化读透

Leire Torices1, Caroline E Nunes-Xavier1,2,3, Rafael Pulido1,3,4

  • 1Biobizkaia Health Research Institute, 48903 Barakaldo, Spain.

Cancers
|August 29, 2024
PubMed
概括

研究人员发现,特定的药物组合可以恢复PTEN-L的功能,这是一种涉及PTEN hamartoma瘤综合征 (PHTS) 的蛋白质变体. 这种方法准了过早终结子 (PTCs),以实现功能性蛋白质的生产.

关键词:
在 PHTS PHTS 中.遗传病是一种遗传性疾病.精密疗法是指精确的治疗方法.过早终止的代码子翻译阅读通过翻译.

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