TLK1>Nek1轴促进核保留和YAP的激活,这对抗割的前列腺癌有影响

Damilola Olatunde1, Arrigo De Benedetti1

  • 1Department of Biochemistry and Molecular Biology, The Feist Weiller Cancer Center, Louisiana State University Health Shreveport, Shreveport, LA 71103, USA.

Cancers
|August 29, 2024
PubMed
概括

用J54准TLK1>NEK1轴通过去酸化YAP并防止其核保留来抑制前列腺癌的进展,为抵抗割的前列腺癌 (CRPC) 提供了一个新的治疗策略.

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