咖啡消费对主观感知和炎症标志物的影响在患有炎症性肠病的患者中
Lidia Neamți1, Simona R Gheorghe1, Amalia Ventuneac2
1Department of Medical Biochemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
咖啡消费在炎症性肠道疾病 (IBD) 患者中很常见. 定期摄入咖啡,特别是天然咖啡,与较低的便calprotectin (FC) 水平有关,这是一个关键的炎症标志物,特别是在性结肠炎 (UC) 中.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 营养科学 营养科学
背景情况:
- 炎症性肠病 (IBD),包括克罗恩病 (CD) 和性结肠炎 (UC),是影响生活质量的慢性炎症性疾病.
- 了解生活方式因素,如咖啡消费,对于管理IBD症状和炎症至关重要.
研究的目的:
- 为了调查CD和UC患者的咖啡消费模式.
- 评估咖啡对IBD感知症状和客观炎症标志物的影响.
- 探索CD和UC之间这些影响的潜在差异.
主要方法:
- 一项涉及148名IBD患者 (CD和UC) 的研究.
- 通过问卷收集关于咖啡消费和感知症状影响的数据.
- 测量炎症标志物:白细胞,C反应蛋白 (CRP),红细胞沉积率 (ESR) 和便calprotectin (FC).
主要成果:
- 60%的IBD患者报告经常喝咖啡,CD和UC组之间没有显著差异.
- 在咖啡消费者与非消费者之间观察到较低的便calprotectin (FC) 水平 (p < 0.05).
- 自然咖啡 (p < 0.001) 和特别是性结肠炎患者 (p < 0.05) 中,CF的减少更为明显.
结论:
- 在IBD患者中,咖啡消费很普遍.
- 咖啡摄入量,特别是天然咖啡,与便中calprotectin水平的降低有关,这表明在肠道中具有潜在的抗炎作用.
- 需要进一步的研究来阐明咖啡对IBD肠道炎症的影响背后的机制,特别是在UC.
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