探索从两个安第斯山脉果中分离出来的安托西亚宁的多面生物活动
Carlos Barba-Ostria1, Saskya E Carrera-Pacheco2, Rebeca Gonzalez-Pastor2
1Escuela de Medicina, Colegio de Ciencias de la Salud, Universidad San Francisco de Quito USFQ, Quito 170901, Ecuador.
Foods (Basel, Switzerland)
|August 29, 2024
概括
来自安第斯蓝和黑的安托西亚宁显示出强大的抗菌,抗氧化和抗炎作用. 这些天然颜料为药品和营养食品提供了有前途的治疗潜力.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
背景情况:
- 天然颜料,如安东素,广泛用于食品,化品和制药.
- 安第斯蓝 (Vaccinium floribundum) 和安第斯黑 (Rubus glaucus) 是丰富的酸盐的来源.
研究的目的:
- 评估来自安第斯山脉果的安东素的综合生物活动.
- 评估它们在制药和营养食品应用中的潜力.
主要方法:
- 使用质谱法进行化学表征.
- 抗微生物测试以确定最小抑制度 (MIC).
- 抗氧化能力,抗瘤,抗炎和溶血活性评估.
主要成果:
- 鉴定出具有显著的安托西亚宁含量,具有多样化的糖化模式.
- 有效的抗微生物活性对抗格拉姆阳性细菌 (MIC低至1毫克/毫升的Rubus Glaucus).
- 显著的抗氧化能力,显著的抗瘤和抗炎作用 (氧化抑制) 和不同的溶血活性.
结论:
- 安第斯山果的安托西亚宁具有强大的生物活性,包括抗微生物,抗氧化,抗瘤和抗炎性质.
- 花没有显著的溶血活性,表明安全性.
- 这些发现支持安第斯山脉果中的安东素在制药和营养食品应用中的使用.
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