最多的氧气消耗与面额骨骨缩症中的脂肪质量有负面关联
Oscar Crisafulli1, Luca Grattarola1, Giorgio Bottoni1
1CRIAMS-Sport Medicine Centre Voghera, University of Pavia, 27058 Voghera, Italy.
概括
面骨骨缩症 (FSHD) 患者表现出心肺呼吸能力 (VO2max) 的降低,与较高的身体脂肪,BMI,体重和年龄有关. 这些体质成分标记可以帮助FSHD的临床评估.
科学领域:
- 神经肌肉疾病 神经肌肉疾病
- 运动生理学 运动生理学
- 身体组成分析 身体成分分析
背景情况:
- 面骨骨缩症 (FSHD) 导致逐渐的肌肉损失和身体脂肪增加.
- 通过最大氧气消耗 (VO2max) 表示的心脏呼吸能力,是关键的健康指标.
- 测量VO2max在FSHD患者中可能是具有挑战性的,因为运动不耐受.
研究的目的:
- 在FSHD患者中调查人体/人体组成参数与VO2max之间的关联.
- 为了确定FSHD临床分层的易于测量的参数.
- 了解身体构成对FSHD运动能力的影响.
主要方法:
- 招募了22名基因确诊FSHD的个人.
- 在循环人体计上使用心肺运动测试 (CPET) 评估VO2max.
- 通过生物电阻分析 (BIA) 测量体重,身高 (BMI) 和身体成分 (脂肪质量,无脂肪质量,体细胞质量).
主要成果:
- VO2max与脂肪质量 (SCC -0.712),BMI (SCC -0.673),年龄 (SCC -0.480) 和体重 (SCC -0.634) 有显著的负相关性.
- 在VO2max和无脂肪质量或体细胞质量之间没有发现显著的关联.
- 较高的脂肪和BMI与FSHD中较低的心肺呼吸能力有关.
结论:
- 脂肪质量,BMI,年龄和体重与FSHD的VO2max负相关.
- 这些人体结构和人体结构参数可以作为评估FSHD功能能力的实际指标.
- 结果支持使用这些易于获得的措施来改善FSHD患者的临床分层.
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