骨质疏松症作为女性特异性风险因子,导致2型糖尿病的老年患者发动性衰竭
Chieh-Hua Lu1, Sheng-Chiang Su1, Feng-Chih Kuo1
1Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.
Journal of clinical medicine
|August 29, 2024
概括
骨质疏松症和肌力衰竭经常在患有2型糖尿病的老年女性中同时发生. 增加的体重指数 (BMI) 和骨质疏松症是这个人群中发动性的重要危险因素.
科学领域:
- 老年学是指老年学的学科.
- 内分泌学 在内分泌学.
- 骨和矿物质的新陈代谢.
背景情况:
- 肌力衰弱 (与年龄相关的肌肉衰弱) 增加了跌倒的风险.
- 骨质疏松症在老年人中普遍存在,尤其是女性.
- 在老年人中,肌,骨质疏松症和2型糖尿病 (T2DM) 之间的相互作用尚未得到充分理解.
研究的目的:
- 在T2DM患者中调查骨质疏松症和骨质疏松症之间的关联.
- 专注于患有T2DM的老年女性,因为她们的骨质疏松症患病率较高.
主要方法:
- 对103名T2DM患者 (50-80岁) 的横截面研究.
- 双能X射线吸收计 (DXA) 用于身体组成和骨质疏松症评估.
- 测量手握强度以评估动力障碍症,以性别特定的方式分析.
主要成果:
- 在女性T2DM患者中观察到较高的动脉和动脉骨质疏松症的患病率.
- 骨质疏松症和骨质疏松症之间的显著正相关性,即使在BMI调整后.
- 多变量分析确定BMI (OR 1.234) 和骨质疏松症 (OR 4.883) 是T2DM女性发动性的风险预测因素.
结论:
- 在T2DM患者中,骨质疏松症和骨质疏松症的高女性特异性共发生率.
- 骨质疏松症和BMI升高是T2DM的老年妇女中发展动脉的潜在危险因素.
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