在高或低风险患抑郁症的年轻成年人中,短期血压变化
Balázs Bence Nyárády1, Miklós Vértes2, Edit Dósa1
1Heart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary.
患有抑郁病史的年轻人表现出血压变化 (BPV) 的增加,这与抑郁症发作数量有关. 在这些人中,早期监测BPV可能有助于预防未来的心血管疾病.
科学领域:
- 心血管健康 心血管健康
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 抑郁症与不良血压 (BP) 影响和高血压变化 (BPV) 有关.
- 高短期BPV与心血管风险增加有关.
- 抑郁症对年轻成年人BPV的早期影响尚不清楚.
研究的目的:
- 调查抑郁症对BPV的有害影响是否在年轻成人时可以辨认出来.
- 确定抑郁症的高风险是否会影响BPV.
- 检查是否临床抑郁特征适度其对BPV的不良影响.
主要方法:
- 研究了218名患有重度抑郁症的试验者,206名高风险的兄弟姐妹和166名对照.
- 进行了精神病学评估和三次标准化血压测量.
- 定义的短期BPV为BP测量之间的范围.
主要成果:
- 在连续的测量中,静缩和腹缩血压下降.
- 在对照年龄后,在BPV中没有发现任何显著的群体差异.
- 终身抑郁情节的数量预测了更高的透静血压.
结论:
- 抑郁症对BPV的不良影响在年轻成年人的群体水平上并不明显.
- 终身抑郁负担,以情节数量为指标,预测BPV增加.
- 对有抑郁病史的年轻成年人进行BPV监测可以帮助早期预防心血管疾病.
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