患有慢性渐进性外部眼膜的患者的麻醉概念 接受眼科手术-回顾性队列分析
Nicolas Leister1, Stefanie Wendt2, Andrea Hedergott3
1Department of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Köln, Germany.
Journal of clinical medicine
|August 29, 2024
概括
对于正在接受眼科手术的慢性渐进性外部眼 (CPEO) 患者的麻醉,在局部和全身麻醉下都是可行的. 在全身麻醉期间,对CPEO患者来说,短期使用普罗波似乎是安全的.
科学领域:
- 麻醉学 麻醉学
- 神经学 神经学
- 眼科医生 眼科 眼科
背景情况:
- 慢性渐进性外部眼膜 (CPEO) 是一种线粒体疾病.
- 对于CPEO患者的麻醉,由于药物对线粒体代谢的影响,存在风险.
- 眼科手术需要对CPEO患者进行仔细的麻醉规划.
研究的目的:
- 评估CPEO患者眼科手术的麻醉策略.
- 在这个人群中评估局部和全身麻醉的安全性和可行性.
主要方法:
- 追溯的,单心的队列分析.
- 11名CPEO成年患者接受眼科手术 (2012年1月 - 2022年2月).
- 局部麻醉 (LA) 和全身麻醉 (GA) 队列的比较.
主要成果:
- 进行了12次眼科手术:在LA下6次,在GA下6次.
- 涉及的GA包括福尔/雷米芬坦尼尔或德斯弗兰/雷米芬坦尼尔.
- 平均GA持续时间为37.5分钟;恢复时间为48.5分钟.
- 在LA或GA组中没有显著的并发症.
- 所有在术后第一天出院的患者.
结论:
- 局部和全身麻醉都是CPEO患者眼科手术的可行选择.
- 在CPEO患者中,普罗波是一种可行的短时间 (<1小时) 的催眠剂.
- 仔细的麻醉管理确保了CPEO患者接受眼科手术的安全结果.
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