使用Nexobrid®进行深层手烧的酶分解后的长期功能结果:回顾性分析
Asja T Malsagova1, Amin El-Habbassi2, Moritz Billner1
1Department for Plastic, Reconstructive and Hand Surgery, Burn Center for Severe Burn Injuries, Nuremberg Hospital, Paracelsus Medical University, Breslauer Str. 201, 90471 Nuremberg/Prof.-Ernst-Nathan Straße 1, 90419 Nuremberg, Germany.
Journal of clinical medicine
|August 29, 2024
概括
对于深层手烧伤的酶去化为传统手术提供了一个可行的替代方案. 这种方法,特别是与皮肤替代品相结合时,会导致长期良好的手部功能和患者满意度.
科学领域:
- 手部手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手术手 ...
- 烧伤治疗 烧伤治疗
- 组织再生 组织再生
背景情况:
- 手术除与自移植是严重手烧伤的标准.
- 酶解正在成为一种保留组织的替代方案.
- 选择性组织保护对于最佳的手部功能至关重要.
研究的目的:
- 在深层皮肤烧伤中进行酶解后评估长期的手部功能.
- 为了比较保守管理和自移植后酶脱bridement之间的结果.
- 通过验证的结果措施来评估功能和美学结果.
主要方法:
- 回顾32个酶分离手的回顾性图表审查.
- 身体检查和验证的结果得分 (DASH,POSAS,VSS).
- 评估手的功能 (拳头关闭) 和审美满意度.
主要成果:
- 在24名患者中,平均随访时间为31个月.
- 19只用皮肤替代品保守地管理的手;13只需要自移植.
- 低平均手臂,肩膀和手的残疾 (DASH) 得分为8,在保守管理的组中得分明显更好 (平均4).
- 患者对美学结果的高满意度 (30/30个案例).
- 功能恢复很好,有30/30个案例实现了完全的拳头关闭.
结论:
- 酶去是有效的深度手烧伤.
- 结合酶解脱与保守的皮肤替代品管理,可以获得有利的长期功能和美学效果.
- 与传统方法相比,这种方法可能会减少长期的手部残疾.
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