阴道透视多眼切除术对IVF试管婴儿结果的影响 妇女有不明原因的不孕不育
Olga Triantafyllidou1, Ilias Korompokis1, Stamatia Chasiakou2
12nd Department of Obstetrics and Gynaecology, Aretaieio Hospital, National and Kapodistrian University of Athens, Vas. Sofias Str. 76, 11528 Athens, Greece.
Journal of clinical medicine
|August 29, 2024
概括
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科学领域:
- 生殖医学 生殖医学
- 妇科外科手术 妇科外科
- 不孕症治疗 不孕症治疗
背景情况:
- 子宫内膜聚是不孕不育的潜在原因,可能会对体外受精 (IVF) 的结果产生负面影响.
- 以前的试管婴儿试验可能由于未被诊断或未经治疗的子宫因素而失败,例如子宫内膜息肉.
- 目前正在调查透透镜多角切除术在改善有试管婴儿失败史的女性体外受精成功的疗效.
研究的目的:
- 为了评估透透镜多角切除术对试管婴儿的影响,试管婴儿在不孕妇女中产生了至少一个先前不成功的试管婴儿周期.
- 为了确定通过透视镜去除子宫内膜的息肉是否会提高特定患者队列中的怀孕率.
主要方法:
- 一项回顾性队列研究分析了40名怀疑患有子宫内膜息肉的不孕妇女 (18至45岁),以及先前的IVF失败,不包括男性因素.
- 宫内膜的息肉被通过使用透镜和切除镜去除.
- 所有患者在随后的周期中都接受了卵巢刺激和试管婴儿,使用了短性腺激素释放激素 (GnRH) 抗剂协议.
主要成果:
- 在72.5% (29/40) 的患者中,透透镜多角切除术导致了阳性妊娠测试,其中包括65%的临床和7.5%的生化妊娠.
- 临床怀孕 (p < 0.001) 和总怀孕 (p < 0.001) 的统计学上显著增加在多胞胎切除术后观察到.
- 成功结局的女性年轻,具有有利的荷尔蒙特征 (较低的FSH,更高的AMH,更高的雌激素峰值) 和更好的卵细胞/胚胎产量.
结论:
- 阴道透视多角切除术是一种有效的程序,用于改善怀疑子宫内膜聚质体的妇女的IVF结果,并有IVF失败的历史.
- 这项研究表明,在切除歇斯底里学息肉后,临床和总妊娠率显著改善.
- 这种干预提供了一种有价值的策略,以提高被选中的不育患者的试管婴儿成功率.
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