在食道切除术期间使用印ocyanine绿色可以防止解剖漏洞吗? 系统性审查和元分析
Andrea Sozzi1, Davide Bona1, Marcus Yeow2
1I.R.C.C.S. Ospedale Galeazzi-Sant'Ambrogio, Department of Biomedical Science for Health, Division of General Surgery, University of Milan, 20122 Milano, Italy.
Journal of clinical medicine
|August 29, 2024
概括
印ocyanine Green (ICG) 的评估可能会降低食道切除术后道泄漏 (AL) 的风险. 这次系统性审查发现ICG指导与较低的AL率有关,尽管由于研究的局限性,需要进一步研究.
科学领域:
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
- 医疗成像医学成像
背景情况:
- 在食道切除术期间,用于评估胃通道和透输液的印ocyanine Green (ICG) 被探索.
- 尽量减少静脉漏 (AL) 是至关重要的,但关于ICG影响的证据有限.
- 这项研究解决了ICG对AL最小化实际影响的尚未解决的问题.
研究的目的:
- 为了比较ICG引导和非ICG引导 (nICG) 的食道胃解剖的短期结果.
- 为了评估ICG在癌症食道切除术后降低术后解性泄漏 (AL) 的有效性.
主要方法:
- 观察性研究的系统审查和元分析.
- 搜索了主要的数据库 (PubMed,Scopus等) 在2024年4月之前.
- 分析了包括1399名患者在内的11项研究,重点关注AL作为主要结局.
主要成果:
- 使用ICG与手术后AL风险降低有关 (RR 0.48;95% CI 0.23-0.99;p=0.05).
- 累计AL发病率为ICG的10.4%,而nICG的15.4%.
- 在肺部并发症,手术时间,住院时间或90天死亡率方面没有发现显著差异.
结论:
- ICG的评估表明,有可能减少食道切除术后的AL.
- 包括研究设计,偏见和异质性在内的局限性需要对ICG的影响进行谨慎的解释.
- 需要进一步的高质量研究来确认ICG在预防AL方面的好处.
关键词:
静体泄漏发生在静体上消化管切除术是指消化管切除术.光是一种光.胃管 perfusion 的胃管 perfusion 的胃管 perfusion 的胃管 perfusion 的胃管 perfusion 的胃管印度氨酸绿色的绿色更多相关视频
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