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Updated: Jun 14, 2025

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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在内皮细胞中,TNF诱导了Laminin-332-编码基因,而Laminin-332促进了无源内皮表型

Assim Hayderi1, Mulugeta Melkie Zegeye1, Sare Meydan1

  • 1Cardiovascular Research Centre, Department of Medical Sciences, School of Medicine, Örebro University, 70362 Örebro, Sweden.

International journal of molecular sciences
|August 29, 2024
PubMed
概括

瘤坏死因子-α (TNF) 增加了内皮细胞中的拉米宁-332 (LN332) 基因表达. LN332损害了内皮的完整性,并促进了白细胞的粘附,这表明它在动脉样硬化中发挥了作用.

关键词:
这是一个ECM,ECM是ECM.激活的内皮细胞被激活.动脉样硬化 动脉样硬化在Laminin-5中使用.单细胞迁移 单细胞迁移

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