在COVID-19大流行之前,期间和之后的RS病毒感染的临床特征
Natsu Ide1, Kyosuke Tabata1,2, Norihiro Tokuma1
1Division of Pediatrics, Tokyo Metropolitan Toshima Hospital, Tokyo 173-0015, Japan.
Children (Basel, Switzerland)
|August 29, 2024
概括
COVID-19大流行改变了儿童的呼吸道同胞性 (RS) 病毒感染严重程度. 在疫情后,儿童使用氧气和机械通风的比率更高,这表明疾病的严重程度增加.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 在全球范围内,COVID-19大流行影响了传染病模式.
- 呼吸道同胞体病毒 (RS) 是一个常见的儿童感染,通常是轻微的.
- 流行病相关的限制可能改变了RS病毒的流行病学和临床表现.
研究的目的:
- 研究COVID-19大流行对儿童RS病毒感染的临床特征的影响.
- 为了比较RS病毒感染的严重程度和管理要求,跨越大流行前,大流行期间和大流行后的时期.
主要方法:
- 在东京大都会东希马医院进行了一项观察性研究.
- 分析了369名RS病毒感染的6岁以下儿童的临床人口统计数据.
- 为了进行比较分析,患者被分为流行病前,流行病期间和流行病后的组.
主要成果:
- 流行病期间和之后的儿童与流行病前组相比,需要氧气支持的几率明显更高.
- 疫情后的小组显著增加了需要机械通风的几率.
- 这些发现表明,在流行后的时代,RS病毒感染的趋势更为严重.
结论:
- COVID-19 流行病和相关的公共卫生措施似乎改变了儿童RS病毒感染的临床过程.
- 疫情后期观察到严重程度增加,氧气使用率和机械通风率更高,这表明疫情严重程度增加.
- 需要进一步的研究来了解这些变化的长期影响.
更多相关视频
08:05Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
14.1K
08:41Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
2.7K
相关概念视频
COPD: Pathogenesis and Clinical Features
244
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
244
Viral Mutations
32.2K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
32.2K
Mechanisms of Retrovirus-induced Cancers
5.1K
Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
5.1K
Stages of Infection
55.9K
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
55.9K
