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在接受口服乳糖酶治疗的婴儿中,应避免使用西美西康药物
Ekin Say Yildirim1, Adem Aydin1, Tolga Ince1
1Department of Pediatrics, Faculty of Medicine, Dokuz Eylül University, 35340 İzmir, Türkiye.
Children (Basel, Switzerland)
|August 29, 2024
概括
在大多数情况下,口服乳糖酶有效治疗婴儿乳糖不耐症. 然而,当它与西美西康一起用于结肠时,其疗效可能会降低,这表明潜在的药物相互作用.
科学领域:
- 儿科 儿科 儿科
- 胃肠病学 胃肠病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 婴儿乳糖不耐症是一种常见的疾病.
- 口服乳糖补充剂是一种潜在的治疗方法.
- 了解影响乳糖酶功效的因素至关重要.
研究的目的:
- 为了评估口服乳糖酶在被诊断为乳糖不耐症的婴儿中的疗效.
- 评估性别,出生体重和同时服用药物对乳糖治疗结果的影响.
- 为了确定影响口服乳糖酶有效性的潜在药物相互作用.
主要方法:
- 对0-6个月龄的婴儿进行了回顾性研究,诊断出乳糖不耐症.
- 数据收集包括人口统计信息,症状发作和使用的药物.
- 基于患者特征和同时服用药物的治疗反应分析.
主要成果:
- 86.7%的婴儿对口服乳糖酶有积极反应.
- 根据性别,出生体重或症状发病时的年龄,没有观察到有效性的显著差异.
- 乳糖酶的有效性随着时间的推移而得到改善,这可能是由于肠道的发育.
- 同时使用西美西康降低了乳糖酶反应,表明了潜在的药物相互作用.
- 益生菌没有影响口服乳糖治疗的有效性.
结论:
- 口服乳糖酶是婴儿乳糖不耐症的有效治疗方法.
- 同时服用西美西康可能会降低口服乳糖酶的疗效.
- 避免使用simethicone等额外的药物与口服乳糖酶同时使用,以确保最佳的治疗结果.
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